Epidemiology and risk factors for diabetes in the suburbs of Beijing: a retrospective cohort study
| Autor: | Bo Zhang, Lingding Xie, Xu Zhao, Haiqing Zhu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty endocrine system diseases Adolescent Epidemiology Overweight Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Diabetes mellitus Glucose Intolerance medicine Humans Cumulative incidence 030212 general & internal medicine Retrospective Studies business.industry Incidence (epidemiology) general diabetes public health Type 2 Diabetes Mellitus nutritional and metabolic diseases Retrospective cohort study General Medicine medicine.disease Diabetes Mellitus Type 2 Beijing Medicine Female medicine.symptom business 030217 neurology & neurosurgery Cohort study Follow-Up Studies |
| Zdroj: | BMJ Open BMJ Open, Vol 11, Iss 3 (2021) |
| ISSN: | 2044-6055 |
| Popis: | ObjectiveWe aimed to detect the incidence and risk factors of type 2 diabetes mellitus (T2DM) development in the suburbs of Beijing.DesignCohort study with record linkage to incidence data.SettingWe performed a 5-year follow-up study in a randomly selected suburban population including 1114 subjects aged ≥18 years living in the suburbs of Beijing.Participants118 subjects with T2DM at baseline according to the 1999 WHO criteria were excluded, and 895 subjects attended the follow-up assessment in 2012. The non-diabetic subjects at baseline were classified into two groups: normal glucose tolerance (NGT) group (n=673) and impaired glucose regulation (IGR) group(n=222).The incidence and risk factors of diabetes development in each group were investigated.Outcome measuresA structured questionnaire about sociodemographic characteristics, height, weight, waist circumference, hip circumference, blood pressure, oral glucose tolerance test and serum lipid levels.ResultsOut of the 895 non-diabetic subjects, 67 developed diabetes with 29 in the NGT group and 38 in the IGR group, respectively, after a 5-year follow-up, producing an overall 5-year cumulative incidence of diabetes of 13%. The incidence of diabetes was 15.5 cases per 1000 person-years, 8.9 cases per 1000 person-years in the NGT group and 35.7 cases per 1000 person-years in the IGR group (pConclusionsDuring a mean follow-up of 5.0 years, the incidence of T2DM in the suburbs of Beijing was 15.5 per 1000 person-years. Early prevention of diabetes should focus on IGR subjects. Elevated FPG predicted diabetes development for both NGT and IGR subjects. Female sex, overweight/obesity and DBP are risk factors for diabetes development in IGR subjects. |
| Databáze: | OpenAIRE |
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