Hepatitis E virus in Tibetan pigs on the Qinghai-Tibetan Plateau: detection, molecular characterization and infection of BALB/c mice
| Autor: | Hua Yue, Qun Zhou, Kelei Zhou, Bin Zhang, Danjiao Yang, Cheng Tang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Swine
viruses medicine.disease_cause Tibet BALB/c Evolution Molecular 03 medical and health sciences Mice Hepatitis E virus Phylogenetics Virology Genetic variation Genotype medicine Prevalence Animals Feces Phylogeny 030304 developmental biology Swine Diseases 0303 health sciences biology Phylogenetic tree 030306 microbiology virus diseases Genetic Variation General Medicine biology.organism_classification digestive system diseases Hepatitis E Diarrhea RNA Viral medicine.symptom |
| Zdroj: | Archives of virology. 164(12) |
| ISSN: | 1432-8798 |
| Popis: | This study was performed to investigate the prevalence and genetic variation of hepatitis E virus (HEV) in Tibetan pigs and to determine its ability to infect mice. A total of 38 out of 229 (16.59%; 95% CI = 12.00%–22.10%) fecal samples from Tibetan pigs from the Qinghai-Tibetan Plateau in 2018 were positive for HEV RNA, which was detected by RT-nPCR. Significantly different detection rates were observed between samples from diarrheic and clinically healthy animals (OR = 9.56; 95% CI, 2.84–32.14; p |
| Databáze: | OpenAIRE |
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