Use of Connected Pen as a Diagnostic Tool to Evaluate Missed Bolus Dosing Behavior in People with Type 1 and Type 2 Diabetes
| Autor: | Howard Wolpert, Eric S. Meadows, Stephanie Edwards, Xuanyao He, Wenjie Wang, Jennal Johnson, David Price, Jiat-Ling Poon, William H. Polonsky |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Blood Glucose Male genetic structures endocrine system diseases Endocrinology Diabetes and Metabolism Type 2 diabetes Connected pen Endocrinology Bolus (medicine) Diabetes mellitus medicine Humans Hypoglycemic Agents Dosing Continuous glucose monitoring Glycated Hemoglobin business.industry Blood Glucose Self-Monitoring nutritional and metabolic diseases Original Articles Middle Aged medicine.disease Medical Laboratory Technology Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Anesthesia Missed bolus dose Female business |
| Zdroj: | Diabetes Technology & Therapeutics |
| ISSN: | 1557-8593 1520-9156 |
| Popis: | Objective: This study used connected pen to determine missed bolus dose (MBD) frequency during masked and unmasked continuous glucose monitoring (CGM) periods and examined its link with time-in-range (TIR), time-above-range (TAR), time-below-range (TBR), and key participant characteristics in people with diabetes. Methods: This was a 12-week, single-arm, exploratory, two-period study for people with type 1 diabetes (T1D) or type 2 diabetes (T2D). The primary objective was to estimate the average number of MBD during masked and real-time CGM use. The secondary objective was to estimate the average percent TIR and its relationship to MBD. An exploratory objective was to investigate the participant characteristics that were associated with MBD. Data were analyzed for differences in MBD by diabetes type and other participant characteristics, by CGM period, and by hypoglycemic fear scores. Results: Participants (n = 64; T1D, n = 38; T2D, n = 26) were 48 ± 11.9 years old and 44% were female. From the masked to the unmasked period, MBD, %TAR, %TBR, and glycated hemoglobin decreased significantly (0.74 MBD/day to 0.62 MBD/day, P = 0.008; 53.6%–48.1%, P = 0.004; 4.49%–2.93%, P |
| Databáze: | OpenAIRE |
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