Office-based CO(2) laser surgery for benign and premalignant laryngeal lesions
| Autor: | Frank J. A. van den Hoogen, Henrieke W. Schutte, Anouk S. Schimberg, Jasmijn M. Herruer, Robert P. Takes, Jimmie Honings, Guido B. van den Broek, David J. Wellenstein |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Larynx Laser surgery medicine.medical_specialty CO2 laser office‐based medicine.medical_treatment Laryngoscopy Laryngology Laryngeal Diseases Topical anesthesia Original Reports medicine Humans Prospective Studies Transoral laser microsurgery Voice Handicap Index Prospective cohort study larynx Office based medicine.diagnostic_test business.industry Middle Aged Surgery Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] medicine.anatomical_structure Ambulatory Surgical Procedures Otorhinolaryngology Lasers Gas Feasibility Studies Female topical anesthesia business Precancerous Conditions Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
| Zdroj: | Laryngoscope, 130, 6, pp. 1503-1507 Laryngoscope, 130, 1503-1507 The Laryngoscope |
| ISSN: | 0023-852X |
| Popis: | Contains fulltext : 220120.pdf (Publisher’s version ) (Open Access) OBJECTIVE: Patients with laryngeal pathology are often treated with CO(2) laser surgery, usually in the operating room under general anesthesia. Although office-based laser surgery using several other laser types has been investigated, prospective studies on office-based CO(2) laser surgery are scarce. Our goal was to investigate the feasibility of office-based CO(2) laser surgery for benign and premalignant laryngeal pathology by analyzing completion rate, safety, effect on voice quality, and success rate (i.e., no residual or recurrent disease). METHODS: A prospective cohort study was performed of 30 consecutive procedures. Inclusion started in June 2016 and was completed in August 2018. Adult patients with clinically benign or premalignant laryngeal lesions who could not undergo transoral laser microsurgery in the operating room under general anesthesia were included. Reasons were either contraindications for general anesthesia, previously failed therapeutic laryngoscopy under general anesthesia, and preference of a procedure under topical anesthesia by the patient. The mean follow-up was 9 months. RESULTS: Thirty procedures were performed in 27 patients (24 males) with an average age of 62 years. Twenty-nine (97%) procedures were fully completed without complications. The mean preoperative Voice Handicap Index (VHI) score (VHI 44) significantly decreased 2 months (VHI 28, P = 0.032) and 6 months (VHI 14, P |
| Databáze: | OpenAIRE |
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