Accuracy of shear wave elastography in characterization of thyroid nodules in children and adolescents

Autor: Ibrahim Al Jabr, Abdulwahab Alyahya, Mohamed Y Daoud, Ossama M. Zakaria, Mohammed Qasem AlAlwan, Ahmed Gaber Hassanein, Mohammed Hazem, Nahla Mohamed Ali Hasan, Abdulrahim A. Alabdulsalam
Rok vydání: 2021
Předmět:
Zdroj: Insights into Imaging
Insights into Imaging, Vol 12, Iss 1, Pp 1-10 (2021)
ISSN: 1869-4101
Popis: Background Thyroid nodules are an important health problem in children and adolescents. They possess a higher risk of malignancy in comparison to adults. This fact forms a great dilemma for clinicians. The aim of this study was to evaluate the reliability of shear wave elastography (SWE) as a non-invasive technique in the characterization of thyroid nodules in children and adolescents. Methods This prospective study included 56 patients with thyroid nodules. All the patients underwent clinical assessment, laboratory investigations, ultrasound, and Doppler examination, followed by an SWE assessment. Statistical analysis was performed and the best cut-off value to differentiate benign from malignant nodules was determined using the ROC curve and AUC. Results Seventy-two nodules were detected in the examined patients (ages ranged from 11 to 19 years, with mean age of 14.89 ± 2.3 years). Fifty-eight nodules (80.6%) were benign, and fourteen nodules (19.4%) were malignant (histopathologically proved). Highly suspicious criteria for prediction of malignancy by ultrasound and Doppler were hypoechoic echopattern, internal or internal and peripheral vascularity, microcalcifications, taller-than-wide dimensions, irregular outlines, and absence of halo (p Conclusion Shear wave elastography is a non-invasive technique that can assist in the diagnosis of malignant thyroid nodules among children and adolescents.
Databáze: OpenAIRE
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