Sleep arousal response to experimental thermal stimulation during sleep in human subjects free of pain and sleep problems
| Autor: | Paolo Marchettini, Christiane Manzini, Gilles Lavigne, C. Castronovo, Marco Zucconi, Salvatore Smirne |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Hot Temperature Pain Audiology Non-rapid eye movement sleep Reference Values Skin Physiological Phenomena medicine Humans Effects of sleep deprivation on cognitive performance Neuroscience of sleep Slow-wave sleep Behavior Sleep Stages Electromyography Chronic pain Electroencephalography medicine.disease Sleep in non-human animals Anesthesiology and Pain Medicine Neurology Anesthesia Mental Recall Female Neurology (clinical) Arousal Sleep K-complex Psychology |
| Zdroj: | Pain. 84:283-290 |
| ISSN: | 0304-3959 |
| DOI: | 10.1016/s0304-3959(99)00213-4 |
| Popis: | Although the interaction between sleep and pain is generating considerable interest (NIH Technology Assessment Panel, 1996), it is still unknown if chronic pain is the cause or effect of poor sleep. To further this understanding, subjects free of pain and sleep problems need to be studied in order to assess their response to pain during sleep, defined as a behavioral and a physiological state in which sensory processing is altered. (For example, while auditory perception remains active, other sensory inputs are facilitated, attenuated, or suppressed (Velluti, 199746 degrees C) was statistically greater in the lighter sleep stage 2 (48.3%) than in the deeper stages 3&4 (27.9%). A nocifensive behavioral-motor response was associated with only 2.5% of the 351 heat pain stimuli. Two other markers of sleep quality-sleep stage shift and awakening-were not influenced by the thermal stimuli. None of the subjects demonstrated any burns in the morning following the thermal stimulations applied during sleep. We conclude that the processing of nociceptive inputs is attenuated across sleep stages. |
| Databáze: | OpenAIRE |
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