Quality of life in inflammatory neuropathies : the IN-QoL
| Autor: | Draak, T.H., Faber, C.G., Merkies, I.S., Raaphorst, J., Schaik, I.N. van, Visser, M de |
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| Přispěvatelé: | MUMC+: MA AIOS Neurologie (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Neurologie (9), Klinische Neurowetenschappen |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Visual Analog Scale Minimal Clinically Important Difference Paraproteinemias 1ST REVISION 0302 clinical medicine Quality of life HEALTH SURVEY SF-36 PARKINSONS-DISEASE Surveys and Questionnaires 030212 general & internal medicine PERIPHERAL-NERVE-SOCIETY Guillain-Barre syndrome NEUROLOGICAL-SOCIETIES Peripheral Nervous System Diseases Middle Aged IMPAIRMENT Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] humanities DOENÇAS AUTOIMUNES Psychiatry and Mental health GUILLAIN-BARRE-SYNDROME Female JOINT TASK-FORCE EUROPEAN-FEDERATION Adult medicine.medical_specialty Adolescent Visual analogue scale Guillain-Barre Syndrome 03 medical and health sciences Young Adult ORDINAL SCALES medicine Humans In patient Aged Rasch model business.industry Reproducibility of Results Polyradiculoneuropathy medicine.disease Peripheral neuropathy Polyradiculoneuropathy Chronic Inflammatory Demyelinating Physical therapy Quality of Life Surgery Neurology (clinical) business Factor Analysis Statistical 030217 neurology & neurosurgery Multifocal motor neuropathy |
| Zdroj: | Journal of Neurology Neurosurgery and Psychiatry, 89(3), 256-262. BMJ Publishing Group Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Journal of Neurology, Neurosurgery and Psychiatry, 89(3), 256. BMJ Publishing Group Journal of Neurology, Neurosurgery, and Psychiatry, 89, 256-262 Journal of Neurology, Neurosurgery, and Psychiatry, 89, 3, pp. 256-262 |
| ISSN: | 0022-3050 |
| DOI: | 10.1136/jnnp-2017-316634 |
| Popis: | BackgroundNo consensus exists which quality of life (QoL) measure should be used in patients with inflammatory neuropathies. Moreover, most QoL measures are ordinal-based scales with their known deficiencies.ObjectivesTo establish a new disease-specific interval-based QoL questionnaire in inflammatory neuropathies (IN-QoL) using the Rasch model and evaluate its scientific properties (validity, reliability and responsiveness).Methods264 patients with inflammatory neuropathies completed six commonly used QoL questionnaires. The obtained data were stacked and subjected to Rasch analysis. Responsiveness was determined by using the concept of minimum clinically important differences related to varying individually obtained SEs (responsiveness definition: MCID-SE≥1.96 after 1-year follow-up compared with baseline).ResultsThe IN-QoL fulfilled all Rasch’s model requirements with high internal reliability values (patient separation index of 0.94), except being multidimensional. Additional factor analysis resulted in two (functional and mental) subsets that were unidimensional on their own. The IN-QoL showed good correlation with the EuroQol-health quality visual analogue scale (EQ-VAS) (Spearman’s rho 0.72). It demonstrated acceptable responsiveness in patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), as did the EQ-VAS. In patients with monoclonal gammopathy-related neuropathy and multifocal motor neuropathy, hardly any changes were seen over time.ConclusionThe IN-QoL questionnaire fulfils modern clinimetric requirements and correlates strongly with a patient’s self-assessment of their own quality of health, while also showing responsiveness in patients with GBS and CIDP. We propose using the IN-QoL and the EQ-VAS for assessing the QoL of patients with inflammatory neuropathies in future studies. |
| Databáze: | OpenAIRE |
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