Mini-invasive surgical instruments in transaortic myectomy for hypertrophic obstructive cardiomyopathy: a single-center experience with 168 cases

Autor: Ye Yang, Yulin Wang, WenJun Ding, Li Min Xia, Hao Lai, Chun Sheng Wang, Qiang Ji
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
lcsh:Surgery
030204 cardiovascular system & hematology
Single Center
Obstructive cardiomyopathy
lcsh:RD78.3-87.3
03 medical and health sciences
Mini invasive surgery
0302 clinical medicine
Hypertrophic obstructive cardiomyopathy
Heart Septum
Left ventricular outflow tract gradient
Humans
Medicine
030212 general & internal medicine
Cardiac Surgical Procedures
Mitral regurgitation
business.industry
Endovascular Procedures
Mini-invasive surgical instruments
General Medicine
lcsh:RD1-811
Cardiomyopathy
Hypertrophic

Middle Aged
Plastic Surgery Procedures
Septal myectomy
medicine.disease
Surgery
Cardiac surgery
Treatment Outcome
Cardiothoracic surgery
lcsh:Anesthesiology
Female
Cardiology and Cardiovascular Medicine
business
Atrioventricular block
Research Article
Zdroj: Journal of Cardiothoracic Surgery, Vol 16, Iss 1, Pp 1-8 (2021)
Journal of Cardiothoracic Surgery
ISSN: 1749-8090
Popis: Background Although septal myectomy is a standard strategy for managing patients with hypertrophic obstructive cardiomyopathy (HOCM) and drug-refractory symptoms, so far, only a few experienced myectomy centers exist globally. Mainly, this can be explained by the many technical challenges presented by myectomy. From our clinical experience, applying the mini-invasive surgical instruments during myectomy potentially reduces the technical difficulty. This study reports the preliminary experience regarding transaortic septal myectomy using mini-invasive surgical instruments for managing patients with HOCM and drug-refractory symptoms; also, we evaluate the early results following myectomy. Methods Between March 2016 and March 2019, consecutive HOCM patients who underwent isolated transaortic septal myectomy using the mini-invasive surgical instruments were enrolled in this analysis. Intraoperative, in-hospital and follow-up results were analyzed. Results We included 168 eligible patients (83 males, mean 56.8 ± 12.3 years). The midventricular obstruction was recorded in 7 (4.2%) patients. All patients underwent transaortic septal myectomy with a mean aortic cross-clamping time of 36.0 ± 8.1 min. During myectomy, 9 (5.4%) patients received repeat aortic cross-clamping. Surgical mortality was 0.6%. Notably, 5 (3.0%) patients developed complete atrioventricular block, they needed permanent pacemaker implantation. The median follow-up time was 6 months; however, no follow-up deaths occurred with a significant improvement in New York Heart Association functional status. We reported a sharp decrease in the maximum gradients from the preoperative value (11.6 ± 7.4 mmHg vs. 94.4 ± 22.6 mmHg, p p p Conclusions Mini-invasive surgical instruments may be beneficial in reducing the technical challenges of transaortic septal myectomy procedure. Of note, transaortic septal myectomy using the mini-invasive surgical instruments may present with favorable results.
Databáze: OpenAIRE