Artificial Intelligence and Cancer Drug Development
| Autor: | Hong-Yu Li, Fan Yang, Mary Qu Yang, Jerry D Darsey, Shanzhi Wang, Anindya Ghosh |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Cancer Research
Drug discovery business.industry Cancer drugs Big data Antineoplastic Agents General Medicine Data science Bench to bedside Machine Learning Human health Drug repositioning Drug Development Oncology Drug development Artificial Intelligence Neoplasms Drug Discovery Humans Medicine Pharmacology (medical) business Algorithms |
| Zdroj: | Recent Patents on Anti-Cancer Drug Discovery. 17:2-8 |
| ISSN: | 1574-8928 |
| DOI: | 10.2174/1574892816666210728123758 |
| Popis: | Background: The development of cancer drugs is among the most focused “bench to bedside activities” to improve human health. Because of the amount of data publicly available to cancer research, drug development for cancers has significantly benefited from big data and Artificial Intelligence (AI). In the meantime, challenges, like curating the data of low quality, remain to be resolved. Objective: This review focused on the recent advancements in and challenges of AI in developing cancer drugs. Method: We discussed target validation, drug repositioning, de novo design, and compounds' synthetic strategies. Results and Conclusion: AI can be applied to all stages during drug development, and some excellent reviews detailing the applications of AI in specific stages are available. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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