Micrometastases in the cervical lymph nodes in esophageal squamous cell carcinoma
| Autor: | Sameer William Qubain, Saburou Nakashima, Masataka Matsumoto, S. Takao, M Baba, Takashi Aikou, Shoji Natsugoe |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Esophageal Neoplasms Lymph node metastasis Esophageal squamous cell carcinoma medicine Carcinoma Humans Lymph node Aged business.industry Micrometastasis Ultrasound Gastroenterology General Medicine Middle Aged medicine.disease Immunohistochemistry medicine.anatomical_structure Cervical lymph nodes Lymphatic Metastasis Carcinoma Squamous Cell Keratins Lymph Node Excision Female Lymph Nodes Ultrasonography business Neck |
| Zdroj: | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 14(2) |
| ISSN: | 1120-8694 |
| Popis: | Few studies have investigated the presence of lymph node micrometastases (MM) in the cervical region of patients with esophageal squamous cell cancer. The present study examines the presence of cervical MM and attempts to determine a way to predict the occurrence and site of such micrometastases. A total of 2203 cervical lymph nodes and 118 mediastinal recurrent nerve nodes obtained from 86 patients with esophageal carcinoma were examined immunohistochemically using cytokeratins. Cervical lymph nodes and mediastinal recurrent nerve nodes metastases were detected histologically in 33 and 41 of the 86 patients respectively. Cervical lymph node and mediastinal recurrent nerve node MM were immunohistochemically detected in 16 (18.6%) and 6 (7.0%) patients respectively. Of these 16 patients with cervical MM, seven were found to have lymph node metastases in different cervical regions, whereas cervical MM only were detected in nine patients. Among the former group of patients, five were diagnosed by ultrasound examination as having cervical lymph node metastases. Mediastinal recurrent nerve node metastases and MM correlated with the presence of cervical MM in all but one patient. Cervical lymph node metastasis, including micrometastasis, can be predicted by preoperative ultrasonography and the routine histologic examination of mediastinal recurrent nerve nodes. |
| Databáze: | OpenAIRE |
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