Intubation Attempts Increase the Risk for Severe Intraventricular Hemorrhage in Preterm Infants-A Retrospective Cohort Study
Autor: | Neil N. Finer, Yvonne E. Vaucher, James A. Proudfoot, Juin Yee Kong, Mallory A. Boutin, Charles W. Sauer, Tina A. Leone |
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Rok vydání: | 2016 |
Předmět: |
Male
Risk Pediatrics medicine.medical_specialty Neonatal intensive care unit medicine.medical_treatment Birth weight Cohort Studies 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intensive Care Units Neonatal medicine Intubation Intratracheal Intubation Humans Infant Very Low Birth Weight 030212 general & internal medicine Prospective cohort study Cerebral Hemorrhage Retrospective Studies business.industry Incidence (epidemiology) Infant Newborn Retrospective cohort study medicine.disease Intraventricular hemorrhage Pediatrics Perinatology and Child Health Female business Infant Premature Cohort study |
Zdroj: | The Journal of pediatrics. 177 |
ISSN: | 1097-6833 |
Popis: | To evaluate whether neonates exposed to multiple intubation attempts within the first 4 days after birth have an increased incidence of intraventricular hemorrhage (IVH).This is a retrospective cohort study of infants intubated during the first 4 days after birth. Infants had birth weights (BWs) less than 1500 g and were admitted to the neonatal intensive care unit (NICU) at the University of California, San Diego, between January 1, 2005, and July 30, 2009. A subgroup analysis was done for infants with BW less than 750 g.A total of 308 infants with BW 1500 g, including 102 with a BW750 g, were intubated within the first 4 days of life. The number of intubation attempts was significantly greater in infants with a BW750 g who had severe IVH compared with those with mild or no IVH (OR 1.395, 95% CI 1.090-1.786, P = .008). For infants with BW1500 g, the number of intubation attempts in the delivery room was significantly greater for infants with severe IVH (OR 1.317, 95% CI 1.052-1.649, P = .016).Increased intubation attempts were associated with increased incidence of severe IVH in infants with BW less than 750 g and in infants less than 1500 g who were intubated only in the delivery room. Prospective studies are needed to further evaluate the relationship between intubation attempts and severe IVH. |
Databáze: | OpenAIRE |
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