Polyamine inhibition of the conversion of human proacrosin to acrosin

Autor:	R. F. Parrish, Kenneth L. Polakoski, J. C. Goodpasture, L. J. D. Zaneveld
Rok vydání:	1979
Předmět:	Embryology Cadaverine Acrosin Enzyme Precursors BOAR Obstetrics and Gynecology Spermine Cell Biology Spermidine Enzyme Activation chemistry.chemical_compound Endocrinology Reproductive Medicine chemistry Biochemistry Depression Chemical Endopeptidases Putrescine Polyamines Humans Polyamine
Zdroj:	Journal of reproduction and fertility. 57(1)
ISSN:	0022-4251
Popis:	The conversion of human proacrosin to acrosin was inhibited by polyamines. The order of effectiveness was spermine greater than spermidine greater than cadaverine greater than putrescine greater than 1,3,-diaminopropane. These results are similar to those obtained for the conversion of boar proacrosin to acrosin. Unlike the effects on boar acrosin, however, polyamines did not affect the esterolytic activity of human acrosin but had a slight stimulatory effect on the proteolytic activity of human acrosin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a770c786a4ab697182418db2d6a2653 https://pubmed.ncbi.nlm.nih.gov/513005 Zobrazit plný text záznamu