Evaluation of prognosis and nephrotoxicity in patients treated with colistin in intensive care unit

Autor:	Birol Baysal, Enver Yuksel, Emrah Gunay, Şafak Kaya, Eşref Araç
Rok vydání:	2020
Předmět:	Adult Male medicine.medical_specialty Time Factors Turkey Critical Illness lcsh:RC870-923 Critical Care and Intensive Care Medicine intensive care unit law.invention Nephrotoxicity Risk Factors law polycyclic compounds Humans Medicine In patient colistin Adverse effect Intensive care medicine APACHE Aged Retrospective Studies Aged 80 and over business.industry nephrotoxicity Acute kidney injury General Medicine Middle Aged biochemical phenomena metabolism and nutrition Prognosis lcsh:Diseases of the genitourinary system. Urology medicine.disease mortality Intensive care unit Anti-Bacterial Agents Intensive Care Units acute kidney injury Nephrology Clinical Study Colistin Administration Intravenous Female lipids (amino acids peptides and proteins) business Research Article medicine.drug
Zdroj:	Renal Failure, Vol 42, Iss 1, Pp 704-709 (2020) Renal Failure article-version (VoR) Version of Record
ISSN:	1525-6049 0886-022X
DOI:	10.1080/0886022x.2020.1795878
Popis:	Introduction Nephrotoxicity is the most important adverse effect of colistin therapy. We investigated the frequency of nephrotoxicity, risk factors related to nephrotoxicity, and its relationship with mortality in patients who received intravenous colistin in intensive care units (ICUs). Materials and methods We retrospectively reviewed the data of patients who received intravenous colistin in ICUs between 2011 and 2017. Acute kidney injury (AKI) diagnosis and staging were made based on the Kidney Disease Improving Global Outcome criteria. Results There were 149 patients included in the study with 61% being male. The mean age was 58.7 ± 20.3 years. AKI was detected in 96 (64.4%) patients. There were 25 patients with AKI stage 1 (16.8%) and 71 patients with AKI stage 2 or 3 (47.7%). Advanced age (65.0 vs. 47.4 years; p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b915d0cf23590be9722f57aba59f08 https://doi.org/10.1080/0886022x.2020.1795878 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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