Complicated postoperative course in isolated tricuspid valve surgery: looking for predictors

Autor: Andrea Blasio, Michele De Bonis, Fabrizio Monaco, Ottavio Alfieri, Stefania Ruggeri, Alessandra Sala, Davide Schiavi, Marta Bargagna, Roberta Meneghin, Roberto Lorusso, Alessandro Castiglioni, Paolo Denti, Andrea Giacomini, Nicola Buzzatti, Mara Scandroglio, Elisabetta Lapenna, Eustachio Agricola, Davide Carino
Přispěvatelé: CTC, MUMC+: MA Med Staf Spec CTC (9), RS: Carim - V04 Surgical intervention, Sala, Alessandra, Lorusso, Roberto, Bargagna, Marta, Ruggeri, Stefania, Buzzatti, Nicola, Scandroglio, Mara, Monaco, Fabrizio, Agricola, Eustachio, Giacomini, Andrea, Carino, Davide, Meneghin, Roberta, Schiavi, Davide, Lapenna, Elisabetta, Denti, Paolo, Blasio, Andrea, Alfieri, Ottavio, Castiglioni, Alessandro, De Bonis, Michele
Rok vydání: 2021
Předmět:
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Multivariate analysis
SOCIETY
Disease
030204 cardiovascular system & hematology
DISEASE
RECOMMENDATIONS
law.invention
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
law
Ascites
medicine
Humans
tricuspid replacement
tricuspid regurgitation
Retrospective Studies
Heart Valve Prosthesis Implantation
EUROPEAN ASSOCIATION
OUTCOMES
Univariate analysis
Tricuspid valve
hospital outcome
business.industry
isolated tricuspid valve surgery
medicine.disease
TRENDS
Intensive care unit
Tricuspid Valve Insufficiency
Surgery
tricuspid repair
Treatment Outcome
medicine.anatomical_structure
030228 respiratory system
Heart failure
HEART
Tricuspid Valve
medicine.symptom
Cardiology and Cardiovascular Medicine
business
NATIVE VALVULAR REGURGITATION
Kidney disease
Zdroj: Journal of Cardiac Surgery, 36(9), 3092-3099. Wiley
ISSN: 0886-0440
DOI: 10.22541/au.162127343.38741663/v1
Popis: Background This study aims at better defining the profile of patients with a complicated versus noncomplicated postoperative course following isolated tricuspid valve (TV) surgery to identify predictors of a favorable/unfavorable hospital outcome.Methods All patients treated with isolated tricuspid surgery from March 1997 to January 2020 at our institution were retrospectively reviewed. Considering the complexity of most of these patients, a regular postoperative course was arbitrarily defined as a length-of-stay in intensive care unit less than 4 days and/or postoperative length-of-stay less than 10days. Patients were therefore divided accordingly in two groups.Results One hundred and seventy-two patients were considered, among whom 97 (56.3%) had a regular (REG) and 75 (43.6%) a non-regular (NEG) postoperative course. The latter had worse baseline clinical and echocardiographic characteristics, with higher rate of renal insufficiency, previous heart failure hospitalizations, cardiac operations, and right ventricular dysfunction. NEG patients more frequently needed tricuspid replacement and experienced a greater number of complications (p < .001) and higher in-hospital mortality (13% vs. 0%, p < .001). The majority of these complications were related to more advanced stage of the tricuspid disease. Among most important predictors of a negative outcome univariate analysis identified chronic kidney disease, ascites, previous right heart failure hospitalizations, right ventricular dysfunction, previous cardiac surgeries, TV replacement and higher MELD scores. At multivariate analysis, liver enzymes and diuretics' dose were predictors of complicated postoperative course.Conclusion In isolated TV surgery a complicated postoperative course is observed in patients with more advanced right heart failure and organ damage. Earlier surgical referral is associated to excellent outcomes and should be recommended.
Databáze: OpenAIRE