Phenotypic Alterations in Adrenal Tumor Cultures

Autor:	Gordon H. Sato, Toby Rossman, Stuart Holmes, Vincenzo Buonassisi, Leon Edelstein
Rok vydání:	1965
Předmět:	medicine.medical_specialty Multidisciplinary biology medicine.medical_treatment Serum albumin Adrenocorticotropic hormone Glutamine Steroid hormone Endocrinology Biochemistry Hormone receptor Internal medicine medicine biology.protein Corticotropic cell Endocrine gland Hormone
Zdroj:	Science (New York, N.Y.). 148(3678)
ISSN:	0036-8075
Popis:	Adrenal tumor cells in culture gradually develop a requirement for glutamine and serum albumin in order to produce steroids in response to adrenocorticotropic hormone. Glutamine acts simply as a precursor for a protein or proteins whose synthesis is required for the response to the hormone. Albumin apparently binds steroid hormone products that otherwise would inhibit further biosynthesis of steroids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898492cc363296891f10af34876c8f2d https://pubmed.ncbi.nlm.nih.gov/17819430 Zobrazit plný text záznamu