Transcatheter Closure of Perimembranous Ventricular Septal Defects in Infants and Children Using the Amplatzer Perimembranous Ventricular Septal Defect Occluder
| Autor: | Basil Vasilios D Thanopoulos, Jaap Ottenkamp, Michael L. Rigby, Armine Zarayelyan, Christodoulos Stefanadis, Nico A. Blom, Evangelos Karanasios |
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| Přispěvatelé: | Paediatric Cardiology, ACS - Amsterdam Cardiovascular Sciences |
| Rok vydání: | 2007 |
| Předmět: |
Heart Septal Defects
Ventricular Bradycardia Cardiac Catheterization medicine.medical_specialty Adolescent Heart disease Heart block medicine.medical_treatment Perimembranous ventricular septal defect Internal medicine Complete occlusion medicine Humans Child Cardiac catheterization Heart septal defect business.industry Infant Equipment Design medicine.disease Echocardiography Doppler Color Surgery Europe Treatment Outcome Research Design Child Preschool Device Embolization Cardiology Equipment Failure medicine.symptom Cardiology and Cardiovascular Medicine business Echocardiography Transesophageal Follow-Up Studies |
| Zdroj: | American journal of cardiology, 99(7), 984-989. Elsevier Inc. |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2006.10.062 |
| Popis: | There are very few published reports of the transcatheter closure of perimembranous ventricular septal defects (PMVSDs) using the Amplatzer PMVSD occluder with encouraging initial results. This report presents initial and 1-year results from 54 patients with PMVSDs who underwent transcatheter closure at 5 different institutions with the Amplatzer PMVSD occluder. Sixty-five patients with PMVSDs were enrolled at 5 European centers. Eleven of the 65 patients did not fulfill the patient selection criteria at the initial echocardiographic evaluation or at cardiac catheterization. As a result, a total of 54 patients underwent attempted transcatheter closure using the Amplatzer PMVSD occluder. The median age of the patients was 5.1+/-3.6 years (range 0.3 to 13), and the median weight 18.5+/-10.3 kg (range 5 to 45). Devices were permanently implanted in 49 of 54 patients. Complete occlusion of the communication at 1-year follow-up was observed in 46 of 49 patients (94%). Main early procedural complications included (1) device embolization (2 patients), (2) severe bradycardia with hemodynamic compromise (2 patients), and (3) Mobitz II (2:1) heart block (1 patient). Late procedural complications included complete heart block (1 patient). No other complications were observed during follow-up. In conclusion, the Amplatzer PMVSD occluder is promising device that can be used for transcatheter closure in selected patients with PMVSDs. Further studies and long-term follow-up are required before this technique enters routine clinical practice. |
| Databáze: | OpenAIRE |
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