Gonadal pathogenicity of an infectious bronchitis virus strain from the Massachusetts genotype
| Autor: | Viviane Fongaro Botosso, Bruno Rogério Rui, Nicole Assis Pereira, Antonio Carlos Alessi, Leonardo José Richtzenhain, Hélio José Montassier, Ricardo José Garcia Pereira, Sueli Akemi Taniwaki |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Genotype Infectious bronchitis virus Microbiology Virus 03 medical and health sciences Medical microbiology Media Technology medicine Animals Gonads Tropism Poultry Diseases 030304 developmental biology 0303 health sciences biology Virulence 030306 microbiology Veterinary Microbiology - Research Paper Outbreak Avian infectious bronchitis biology.organism_classification Virology Trachea medicine.anatomical_structure Female Coronavirus Infections Chickens Brazil Respiratory tract |
| Zdroj: | Brazilian Journal of Microbiology |
| ISSN: | 1678-4405 |
| Popis: | An outbreak of infectious bronchitis caused by the IBVPR03 strain of the Massachusetts genotype affected H-120 vaccinated laying hens in South Brazil. We investigated the cross protection of the vaccine by assessing the traqueal ciliostasis, virus recovery, and histopathological changes typically observed in the respiratory tract. Although the IBVPR03 strain is S1-genotyped as Massachusetts with a high genomic similarity to the H-120 vaccine strains, surprisingly, we found no tropism or pathogenicity to the trachea in birds infected with this strain. On the other hand, we observed ovarian and testicle lesions. Here, we show that, despite belonging in the Massachusetts genotype, the IBVPR03 pathotype differs from the expected respiratory pattern, causing instead marked histopathological changes in the gonads, so far not associated with this group. |
| Databáze: | OpenAIRE |
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