Intermittently scanned continuous glucose monitoring is associated with high satisfaction but increased HbA1c and weight in well-controlled youth with type 1 diabetes

Autor: Pieter Gillard, Sara Charleer, Kelly Cammaerts, Chantal Mathieu, Kristina Casteels, Eva Vandoorne
Přispěvatelé: Pathology/molecular and cellular medicine, Diabetes Pathology & Therapy, Diabetes Clinic
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Blood Glucose
Male
Pediatrics
medicine.medical_specialty
Adolescent
Child
preschool

Glycated Hemoglobin A/metabolism
Endocrinology
Diabetes and Metabolism

030209 endocrinology & metabolism
Hypoglycemic Agents/therapeutic use
Hypoglycemia
03 medical and health sciences
body weight
0302 clinical medicine
Quality of life
Diabetes mellitus
Blood Glucose Self-Monitoring/methods
Internal Medicine
medicine
Clinical endpoint
Hypoglycemic Agents
Humans
030212 general & internal medicine
Prospective Studies
Child
Quality Of Life
Glycemic
Glycated Hemoglobin
Type 1 diabetes
Blood Glucose/metabolism
business.industry
Blood Glucose Self-Monitoring
Diabetes Mellitus
Type 1/blood

medicine.disease
Diabetes Mellitus
Type 1

Pediatrics
Perinatology and Child Health

Absenteeism
Observational study
Female
business
Popis: OBJECTIVE: We undertook a 24-month prospective observational single-center real-world trial to study impact of access to intermittently scanned continuous glucose monitoring (isCGM) on quality of life (QOL) and glycemic control of youth with type 1 diabetes (T1D). METHODS: Between September 2016 and November 2017, 138 children and adolescents with T1D were recruited. Demographic, metabolic, and QOL data were collected during 24 months of routine follow-up. Primary endpoint was the evolution of QOL, with secondary outcomes change in HbA1c, occurrence of acute diabetes complications, and school absenteeism. RESULTS: Ninety-two percent of participants found isCGM more user-friendly than capillary finger-stick tests and had high treatment satisfaction, without change in diabetes-specific QOL. HbA1c significantly increased from 7.2% (7.0-7.3) (55 mmol/mol [53-56]) at baseline to 7.6% (7.4-7.8) (60 mmol/mol [57-62]) at 12 months (P
Databáze: OpenAIRE