Effects of different Chinese herbal medicines on biochemical parameters in guinea-pig with pigment gallstones
| Autor: | Xue-Lin Zhang, Hong-Gang Gu, Pei-ting Zhu, Jing-Zhe Zhang, Xiao-qiang Liang |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Cholagogues and Choleretics Bilirubin Pigment gallstones Guinea Pigs Gallstones Pharmacology Guinea pig Random Allocation chemistry.chemical_compound Pigment Animals Medicine Bile Pigments Hypodermic injection business.industry Capsule Lincomycin Complementary and alternative medicine chemistry visual_art visual_art.visual_art_medium Calcium business TBIL Drugs Chinese Herbal Phytotherapy medicine.drug |
| Zdroj: | Journal of Chinese Integrative Medicine. 6:856-859 |
| ISSN: | 1672-1977 |
| DOI: | 10.3736/jcim20080816 |
| Popis: | OBJECTIVE To observe the effects of Qingdan Capsule (QDC) and Yanggan Lidan Granule (YGLDG), two kinds of compound traditional Chinese herbal medicines, on biochemical parameters in guinea-pigs with pigment gallstones. METHODS An animal model of pigment gallstones was established in male guinea-pigs by hypodermic injection of lincomycin. The guinea-pigs were randomly divided into blank control group, untreated group, QDC group and YGLDG group. There were 8 guinea-pigs in each group. After ten-day treatment, animals were sacrificed and sampled to calculate the rate of stone formation, total bilirubin (TB), unconjugated bilirubin (UCB) and Ca2+ density in bile of the four groups. RESULTS In comparison with the untreated group, the rates of stone formation in the QDC and YGLDG groups were significantly decreased (P |
| Databáze: | OpenAIRE |
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