Oral loratadine in the management of G-CSF-induced bone pain: a pilot study
| Autor: | Silvie Blazkova, Maura Dowling, Eilis O Leary, Ala Dien Yousif, Caitriona Duggan, Vicky Costello, Louise Murphy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_treatment Administration Oral Pain Pilot Projects G-CSF Loratadine chemotherapy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Neoplasms Granulocyte Colony-Stimulating Factor medicine cancer Humans Bone pain General Nursing Aged Chemotherapy 030504 nursing business.industry Cancer Middle Aged medicine.disease histamine Treatment Outcome chemistry 030220 oncology & carcinogenesis Anesthesia Antihistamine Female Tramadol medicine.symptom Bone Diseases 0305 other medical science business Pegfilgrastim Histamine medicine.drug |
| Zdroj: | British journal of nursing (Mark Allen Publishing). 28(4) |
| ISSN: | 0966-0461 |
| Popis: | This pilot study aimed to ascertain if bone pain induced by granulocyte-colony stimulating factors (G-CSFs) can be alleviated or eliminated by oral antihistamine loratadine. Twelve patients with cancer receiving chemotherapy were included in the study. Daily pain increased between before treatment started and after cycle 1 in all patients. All 12 participants were started on loratadine on cycle 2; three patients were taking pain medications in addition to this as needed, which were ibruprofen (n=1) or tramadol (n=2). Pain decreased towards the later cycles after patients were started on loratadine in cycle 2, with the exception of one patient who also took tramadol as needed in cycle 3. Oral loratadine was found to be associated with pain reduction in patients with cancer receiving G-CSFs. peer-reviewed 2019-08-27 |
| Databáze: | OpenAIRE |
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