Signs of rapidly progressive dementia in a case of intravascular lymphomatosis
| Autor: | Hans A. Kretzschmar, R. Albrecht, R. Lencer, M. Nagel, E. Reusche, Bjarne Krebs |
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| Rok vydání: | 2004 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphoma Autopsy Disease Diagnosis Differential Fatal Outcome Cerebrospinal fluid mental disorders medicine Humans Dementia Pharmacology (medical) Vasculitis Central Nervous System Vascular dementia Biological Psychiatry Aged business.industry Brain General Medicine medicine.disease Non-Hodgkin's lymphoma Psychiatry and Mental health medicine.anatomical_structure 14-3-3 Proteins Disease Progression Female Bone marrow business |
| Zdroj: | European Archives of Psychiatry and Clinical Neuroscience. 255:232-235 |
| ISSN: | 1433-8491 0940-1334 |
| Popis: | Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectrum of syndromes and the absence of circulating lympoma cells in the blood, bone marrow or cerebrospinal fluid in many cases. Here we present IVL in a 78-year-old woman with findings leading to the clinical diagnosis of vascular dementia with sudden beginning and positive 14-3-3 protein in the CSF, commonly reported in Creutzfeldt-Jakob disease (CJD). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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