TEM Derivative-Producing Enterobacter aerogenes Strains: Dissemination of a Prevalent Clone

Autor: Catherine Chanal, Jacques Sirot, D. Sirot, C. De Champs, P. Dumarche, Richard Bonnet
Rok vydání: 2002
Předmět:
Zdroj: Antimicrobial Agents and Chemotherapy. 46:1128-1131
ISSN: 1098-6596
0066-4804
DOI: 10.1128/aac.46.4.1128-1131.2002
Popis: TEM-24 (CAZ-6) extended-spectrum β-lactamase (ESBL) was detected in 1988 in Clermont-Ferrand, France, in Klebsiella pneumoniae ( bla TEM-24 ) and Enterobacter aerogenes ( bla TEM-24b ), and since 1994, a TEM-24-producing E. aerogenes clonal strain has been observed elsewhere in the country. To determine if the spread of this clonal strain was restricted to TEM-24-producing E. aerogenes strains, 84 E. aerogenes strains (non-TEM/SHV-producing strains, TEM-1- or -2-producing strains, and different ESBL-producing strains), isolated from 1988 to 1999 in Clermont-Ferrand ( n = 59) and in 11 other French hospitals in 1998 ( n = 25), were studied. A clonal strain was found for TEM-24- but also for TEM-3- and TEM-1- or 2-producing isolates. This study shows that there is a clonal strain dependent on acquisition of the TEM-type enzyme (TEM-24 and other TEM types).
Databáze: OpenAIRE