IS6110 fingerprinting of sensitive and resistant strains (1991-1992) of Mycobacterium tuberculosis in Colombia
| Autor: | Clara Inés León Franco, Leen Rigouts, Martha Inírida Guerrero, Jorge Enrique Gómez-Marín, Françoise Portaels |
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| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Tuberculosis lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Characterization Human immunodeficiency virus (HIV) lcsh:QR1-502 America Latin Strains Biology Colombia medicine.disease_cause Disease cluster lcsh:Microbiology Microbiology Mycobacterium tuberculosis Polymorphism (computer science) medicine Bacteriology Cluster Analysis Humans Fingerprinting Polymorphism IS6110 medicine.disease biology.organism_classification DNA Fingerprinting Virology Geographic origin DNA Transposable Elements RFLP Restriction fragment length polymorphism Polymorphism Restriction Fragment Length |
| Zdroj: | Europe PubMed Central Memórias do Instituto Oswaldo Cruz., Vol 97, Iss 7, Pp 1005-1008 (2002) Memórias do Instituto Oswaldo Cruz, Volume: 97, Issue: 7, Pages: 1005-1008, Published: OCT 2002 |
| Popis: | The standardized method to study the polymorphism of IS 6110 was used to characterize 53 isolates of Mycobacterium tuberculosis obtained during 1991-1992 from 14 regions in Colombia. In Valle region cluster rate was 25% (4/16). The mean number of IS6110 band was 10 +/- 3. Similarity between strains was of 60% in 81% of strains and this tended to be correlated with geographic origin. For the first time M. tuberculosis without IS6110 bands in restriction fragment length polymorphism analysis was found in Colombia. Additional studies are necessaries in order to best characterize the situation in relation to human immunodeficiency virus epidemic and recent changes in tuberculosis control program. |
| Databáze: | OpenAIRE |
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