Sonographic findings of activeClonorchis sinensis infection
Autor: | Seung Yull Cho, Ren Yuan, Han-Jong Rim, Jae Hoon Lim, Shuyu Wang, Dongil Choi, Sung-Tae Hong, Zhuo Ji |
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Rok vydání: | 2003 |
Předmět: |
Adult
Male China medicine.medical_specialty Pathology Adolescent Endemic Diseases Intrahepatic bile ducts Sensitivity and Specificity Gastroenterology Feces Internal medicine medicine Animals Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Aged Ultrasonography Clonorchis sinensis biology business.industry Gallbladder Ultrasound Echogenicity Middle Aged biology.organism_classification medicine.disease Bile Ducts Intrahepatic Logistic Models medicine.anatomical_structure Liver Clonorchiasis Population study Female business |
Zdroj: | Journal of Clinical Ultrasound. 32:17-23 |
ISSN: | 1097-0096 0091-2751 |
Popis: | Purpose The aim of this study was to document the characteristic sonographic findings of clonorchiasis for the diagnosis of active infection in an endemic area. Methods In a village in northeastern China, residents underwent fecal examinations for detection of Clonorchis sinensis eggs. Shortly thereafter, residents were examined with abdominal sonography. An experienced radiologist performed the sonographic examinations and analyzed the findings. Subjects whose fecal examinations were positive for eggs were considered to have active clonorchiasis; those whose examinations were negative for eggs were used as control subjects. The distinguishing sonographic features of active clonorchiasis were identified by stepwise logistic regression analysis. Results The study population comprised 457 subjects; fecal examinations revealed C. sinensis eggs in 316 and no eggs in 141. Four sonographic findings distinguished subjects with active clonorchiasis from control subjects: increased periductal echogenicity (p < 0.001; R = 0.11; sensitivity, 35%; specificity, 91%), floating echogenic foci in the gallbladder (p < 0.001; R = 0.09; sensitivity, 28%; specificity, 94%), diffuse dilatation of the intrahepatic bile ducts (p < 0.01; R = 0.03; sensitivity, 67%; specificity, 48%), and gallbladder distention (p < 0.05; R = 0.02; sensitivity, 3%; specificity, 100%), in decreasing order of significance. Among these 4 sonographic findings, increased periductal echogenicity and floating echogenic foci in the gallbladder were more significantly associated with active infection than were the other 2. Conclusions Increased periductal echogenicity and floating echogenic foci in the gallbladder were identified as the 2 most significant findings for the sonographic diagnosis of active C. sinensis infection. © 2003 Wiley Periodicals, Inc. J Clin Ultrasound 32:17–23, 2004 |
Databáze: | OpenAIRE |
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