The effect of Valerian on the severity and frequency of hot flashes: A triple-blind randomized clinical trial
| Autor: | Ensiyeh Jenabi, Seyyed Mohammad Mahdi Hazavehei, Ghodratollah Roshanaei, Fatemeh Shobeiri |
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| Rok vydání: | 2017 |
| Předmět: |
Valerian
medicine.medical_specialty Iran Placebo Placebo group Severity of Illness Index law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine medicine Humans 030212 general & internal medicine Herbal supplement 030219 obstetrics & reproductive medicine Postmenopausal women biology business.industry General Medicine Middle Aged biology.organism_classification Mean frequency Clinical trial Treatment Outcome Hot Flashes Physical therapy Female Menopause business |
| Zdroj: | Womenhealth. 58(3) |
| ISSN: | 1541-0331 |
| Popis: | Valerian is one of the most widely used herbal supplements and a phytoestrogenic herb. The aim of this study was to determine the effect of Valerian on the severity and frequency of hot flashes. This triple-blind, randomized, controlled clinical trial was conducted during a three-month period in Hamadan, Iran, in 60 postmenopausal women aged 45-55 years. Participants were randomly assigned to one of two groups- either placebo or Valerian. An oral Valerian 530 mg capsule was given twice per day for two months. An oral placebo 530 mg capsule (starch) was similarly administered. The severity and frequency of hot flashes were determined by the Kupperman index, before the intervention, one month after, and two months after initiation of the intervention. The severity of hot flashes in the Valerian group was significantly lower than that in the placebo group at one (p = .048) and two months (p = .020) after initiation of the intervention. Compared with the placebo group, the mean frequency of hot flashes was significantly reduced two months after initiating the use of Valerian (p = .033). Health-care providers should consider Valerian to be effective for menopausal women with hot flashes. |
| Databáze: | OpenAIRE |
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