Agonistic behavior in groups of limbic epileptic male rats: pattern of brain damage and moderating effects from normal rats
| Autor: | Glenn H. Parker, Lisa L. Cook, Dawn Desjardins, Michael A. Persinger |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Central nervous system Brain damage Muscarinic Agonists Central nervous system disease Epilepsy Limbic system Antimanic Agents Internal medicine Limbic System medicine Agonistic behaviour Animals Rats Wistar Molecular Biology Cerebral Cortex Behavior Animal General Neuroscience Pilocarpine medicine.disease Corpus Striatum Rats Surgery Biting medicine.anatomical_structure Endocrinology Brain Injuries Data Interpretation Statistical Nerve Degeneration Neurology (clinical) medicine.symptom Lithium Chloride Psychology Agonistic Behavior Developmental Biology medicine.drug |
| Zdroj: | Brain Research. 905:26-33 |
| ISSN: | 0006-8993 |
| DOI: | 10.1016/s0006-8993(01)02454-4 |
| Popis: | Different ratios of normal male rats and male rats in which limbic seizures had been induced by a single systemic injection of lithium and pilocarpine were housed in groups of six. The group ratios ranged along the continuum from all normal rats to all experimental rats. The average numbers of episodes of boxing, biting and mounting–thrusting per rat per hour per group were recorded by direct observation (red light) for 1 h during the midscotophase. Groups that contained less than two normal rats exhibited significantly elevated amounts of agonistic (boxing, biting) behavior but not mounting behavior. Multiple regression analyses showed that combinations of neuronal loss within only two to three areas accommodated at least 50% of the variance in the numbers of these behaviors. |
| Databáze: | OpenAIRE |
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