Intracardiac conduction intervals in children with congenital heart disease: comparison of His bundle studies in 41 normal children and 307 patients with congenital cardiac defects
| Autor: | Mary Allen Engle, Klein Aa, J I Haft, Kathryn H. Ehlers, Aaron R. Levin |
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| Rok vydání: | 1977 |
| Předmět: |
Adult
Heart Defects Congenital Heart Septal Defects Ventricular Bundle of His medicine.medical_specialty Time Factors Adolescent Heart disease medicine.medical_treatment Aortic Valve Insufficiency Septum secundum Aortic Coarctation Heart Septal Defects Atrial Electrocardiography Heart Conduction System Heart Rate Physiology (medical) Internal medicine Humans Medicine Cardiac Output Child Ductus Arteriosus Patent Tetralogy of Fallot Cardiac catheterization medicine.diagnostic_test business.industry Infant Mitral Valve Insufficiency Primary interatrial foramen medicine.disease medicine.anatomical_structure Child Preschool Anesthesia cardiovascular system Cardiology Electrical conduction system of the heart Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation. 55:286-294 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/01.cir.55.2.286 |
| Popis: | His bundle electrograms were recorded in 348 patients aged 2 months to 24 years following routine diagnostic cardiac catheterization. Among 41 children found to be free of anatomic or hemodynamic abnormality the following mean values were obtained: P-H interval, 93.4 +/- 15.3 msec; P-A time, 21.2 +/- 7.1 msec; A-H interval, 72.2 +/- 15.9 msec; and H-V interval, 39.8 +/- 5.2 msec. The remaining 307 patients were analyzed by diagnosis of congenital heart disease. The mean P-H interval was found to be significantly increased in both ostium primum and secundum atrial septal defect (ASD) with A-H prolongation in primum ASD and P-A prolongation in secundum ASD. The mean H-V interval was significantly prolonged in ostium primum ASD and in patients with severe aortic stenosis, aortic insufficiency. and mitral regurgitation. Grouping of the patients physiologically revealed that patients with moderate-to-severe right ventricular volume overload had P-H prolongation, and patients with severe left ventricular volume or pressure overload had H-V prolongation. The clinical implications of these findings are discussed. |
| Databáze: | OpenAIRE |
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