Bilateral breast metastases as the first manifestation of an occult pancreatic neuroendocrine tumor
| Autor: | Enrico Armando, Mirella Fasciano, Gisella Lingua, Lucianna Russo, Grazia Ortoleva, Lorenzo Vassallo, Federica Groppo Marchisio, Carla Angela Zavattero |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
R895-920 Octreotide Case Report Metastases Medical physics. Medical radiology. Nuclear medicine Computed Tomography Biopsy medicine Radiology Nuclear Medicine and imaging Breast skin and connective tissue diseases Pancreas Suspicious for Malignancy medicine.diagnostic_test business.industry Breast lumps Occult Magnetic Resonance Imaging medicine.anatomical_structure Radiology Differential diagnosis medicine.symptom business Breast carcinoma Neuroendocrine Tumor medicine.drug |
| Zdroj: | Radiology Case Reports, Vol 16, Iss 12, Pp 3807-3814 (2021) Radiology Case Reports |
| ISSN: | 1930-0433 |
| Popis: | Breast metastases are uncommon findings compared to primary breast cancer and in particular bilateral secondary breast lesions from neuroendocrine tumor (NET)s are extremely rare with just less over 13 cases described in literature. We reported herewith the case of a 54-year-old woman who presented to our Breast Unit after noticing multiple, mobile, bilateral breast lumps. Imaging studies confirmed the presence of multiple, circumscribed, bilateral breast masses with slightly spiculated margins, classified as suspicious for malignancy (BI-RADS 4). A tru-cut biopsy was carried out on the largest lesion of each side and histopathologic and immunohistochemistry examination was consistent with metastases from pancreatic neuroendocrine tumor (PNET). Total-body CT revealed the presence of a mass located in the pancreatic body - tail with associated abdominal lymphadenopathies and multiple secondary nodules in bilateral breast and in the liver. Stage IV disease was diagnosed, patient did not undergo surgery and started LAR – octreotide therapy. Although rare, breast metastases from NETs represent an important diagnostic challenge for practitioners because of the difficulty to differentiate from a primary breast carcinoma or even from benign breast lesions. Clinicians should be aware of the possibility of bilateral breast metastases in differential diagnosis of breast lesions in order to ensure the correct diagnosis and the most appropriate management of these patients. |
| Databáze: | OpenAIRE |
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