Quantitative quasi-static ultrasound elastography using reference layer: Ex-vivo study
| Autor: | Arun K. Thittai, Sathiyamoorthy Selladurai |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Materials science
medicine.diagnostic_test Phantoms Imaging Modulus Stiffness Elasticity Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Elastic Modulus Indentation medicine Elasticity Imaging Techniques 030211 gastroenterology & hepatology Elastography Elasticity (economics) medicine.symptom Ex vivo Quasistatic process Ultrasonography Biomedical engineering |
| Zdroj: | EMBC |
| DOI: | 10.1109/embc.2019.8857352 |
| Popis: | It is well-documented in the literature that changes in tissue elasticity are generally correlated with disease condition. In the case of diffuse liver disease, the elasticity of the liver reduces progressively. However, this change does not clearly manifest in conventional ultrasound examinations. Although quasi-static elastography is popular in clinical applications where qualitative assessment of relative tissue stiffness is enough, its potential is relatively underutilized in liver imaging due to the need for quantitative stiffness value. Recently, it was demonstrated that using a reference layer of known stiffness, one could produce quantitative modulus elastograms of the target tissue using quasi-static elastography using simulations and phantom experiments. Here, we examined the performance of this approach on ex-vivo goat liver samples and compare the estimated modulus values to that obtained from indentation measurements. The results suggest that using this approach of reference layer yields Young's modulus values within 10% error compared to the ground truth. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|