Extramedullary myeloid leukemia: the value of cytogenetic analysis in pediatric orbital tumors
| Autor: | Sumaira A. Arain, Phillip H. Choo, James A Carolan, Daniel C West, Alan M Roth |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Diagnosis Differential Myelogenous Bone Marrow hemic and lymphatic diseases Medicine Humans Child medicine.diagnostic_test business.industry Myeloid leukemia Karyotype General Medicine medicine.disease eye diseases Ophthalmology Leukemia medicine.anatomical_structure Leukemia Myeloid Karyotyping Cytogenetic Analysis Immunohistochemistry Orbital Neoplasms Surgery Bone marrow Sarcoma business Tomography X-Ray Computed |
| Zdroj: | Ophthalmic plastic and reconstructive surgery. 22(2) |
| ISSN: | 0740-9303 |
| Popis: | Orbital extramedullary myeloid tumor, or granulocytic sarcoma, can be difficult to diagnose even with the use immunohistochemical stains, especially if it precedes the development of systemic leukemia. We describe a 6-year-old boy with a rapidly progressive orbital tumor. This patient underwent an orbital biopsy, which was consistent with extramedullary myeloid tumor but not conclusive. Cytogenetic studies on a bone marrow biopsy revealed a translocation consistent with acute myelogenous leukemia. |
| Databáze: | OpenAIRE |
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