Additional Vitamin and Mineral Support for Patients with Severe Burns: A Nationwide Experience from a Catastrophic Color-Dust Explosion Event in Taiwan
| Autor: | Bing-Shiang Yang, Chia Meng Yu, Li-Ru Chen, Chih Ning Chang, Kuo-Hu Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty mineral Adolescent Taiwan Explosions nutritional support lcsh:TX341-641 Lower risk Article Body Mass Index Sepsis Young Adult 03 medical and health sciences chemistry.chemical_compound burns 0302 clinical medicine Blast Injuries Internal medicine Diabetes mellitus Humans Medicine 030212 general & internal medicine Wasting Wound Healing Nutrition and Dietetics business.industry Incidence Incidence (epidemiology) vitamin Dust 030208 emergency & critical care medicine Vitamins medicine.disease Trace Elements chemistry Case-Control Studies Dietary Supplements Wound Infection Hypermetabolism Female medicine.symptom business lcsh:Nutrition. Foods and food supply Total body surface area Food Science |
| Zdroj: | Nutrients Volume 10 Issue 11 Nutrients, Vol 10, Iss 11, p 1782 (2018) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu10111782 |
| Popis: | Major burn injuries, which encompass &ge 20% of the total body surface area (TBSA), are the most severe form of trauma because of the stress response they provoke, which includes hypermetabolism, muscle wasting, and stress-induced diabetes. In 2015, a color-dust explosion disaster occurred in the Formosa Fun Coast of Taiwan and injured 499 people, who were transferred via a nationwide emergency delivery system. Some recommendations are currently available regarding vitamin and mineral support for wound healing and recovery in severe burns, but there is a lack of evidence to confirm the benefits. Thus, the current study aimed to investigate the effects of additional vitamin and mineral support for patients with severe burn injuries. Sixty-one hospitalized individuals with major burns (full thickness and &ge 20% TBSA) were classified into the supplement (n = 30) and control (n = 31) groups, according to whether they received supplementation with additional vitamins, calcium, and magnesium. There were significant differences between the supplement and control groups in the incidence of wound infection (30.0% vs. 77.4%, p < 0.001), sepsis (13.3% vs. 41.9%, p = 0.021), and hospitalization days (51.80 vs. 76.81, p = 0.025). After adjustment, logistic regression analysis revealed that, compared to those in the control group, patients in the supplement group had a lower risk for wound infection (OR 0.11 95% CI 0.03&ndash 0.43 p = 0.002) and sepsis (OR 0.09 95% CI 0.01&ndash 0.61 p = 0.014). Supplementation of multiple vitamins, calcium, and magnesium reduced the risk of wound infection and sepsis, shortened the time of hospitalization, and can be considered for use in major burns. |
| Databáze: | OpenAIRE |
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