Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
| Autor: | Matthias Fellner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
Chemistry media_common.quotation_subject Medicine (miscellaneous) Serine hydrolase RM1-950 medicine.disease_cause Microbiology Chemistry (miscellaneous) Staphylococcus aureus medicine Inhibitor biofilm fluorophosphonate Pharmacology (medical) Therapeutics. Pharmacology General Pharmacology Toxicology and Pharmaceutics media_common |
| Zdroj: | ADMET and DMPK (2021) ADMET and DMPK Volume 10 Issue 2 |
| ISSN: | 1848-7718 |
| Popis: | There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. ©2021 by the authors. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
| Databáze: | OpenAIRE |
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