Pulsed Electromagnetic Fields Increase the Rate of Rat Liver Regeneration after Partial Hepatectomy
| Autor: | Giorgio Piccinini, L. Pernecco, Maria Giuseppina Monti, Bruno Barbiroli, P. Zaniol, A. Ruggeri, Vittoria Ottani |
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| Rok vydání: | 1984 |
| Předmět: |
DNA Replication
Male medicine.medical_specialty Lipid accumulation Haploidy Partial hepatectomy Ornithine Decarboxylase General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Internal medicine medicine Animals chemistry.chemical_classification Glycogen Cell growth Regeneration (biology) Rats Inbred Strains Liver regeneration Liver Regeneration Rats Kinetics Microscopy Electron Enzyme Endocrinology Genes Liver chemistry Rat liver Electromagnetic Phenomena |
| Zdroj: | Experimental Biology and Medicine. 176:371-377 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-176-41885 |
| Popis: | Pulsed extremely low-frequency electromagnetic fields interact with rat liver regeneration following partial hepatectomy when delivered to the rats immediately after the operation and every 12 hr thereafter. This interaction results first in an increased ornithine decarboxylase activity, an enzyme used as an early marker of cell growth. The rate of labeled thymidine incorporation into DNA is also increased by the treatments with magnetic fields during the early phases of liver regeneration. Glycogen depletion and lipid accumulation, two well-known early peculiar phenomena of liver regeneration following partial hepatectomy, are quantitatively decreased by the treatments with electromagnetic fields. The recovery to normal glycogen and lipid contents is completed within 5 days after surgery, instead of 7 days as found in control rats. |
| Databáze: | OpenAIRE |
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