Glycosyl carotenoids from marine spore-forming Bacillus sp. strains are readily bioaccessible and bioavailable ǂ

Autor: Charlotte Sy, Béatrice Gleize, Olivier Dangles, Patrick Borel, Frédéric Carlin, Stéphanie Chamot, Catherine Veyrat
Přispěvatelé: Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Sécurité et Qualité des Produits d'Origine Végétale (SQPOV), Institut National de la Recherche Agronomique (INRA)-Avignon Université (AU), European Project: 207948,EC:FP7:KBBE,FP7-KBBE-2007-1,COLORSPORE(2008), Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Avignon Université (AU)-Institut National de la Recherche Agronomique (INRA), Nutriments Lipidiques et Prévention des Maladies Métaboliques, Université de la Méditerranée - Aix-Marseille 2-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Avignon Université (AU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Agronomique (INRA)-Université de la Méditerranée - Aix-Marseille 2, Borel, Patrick, New Sources of Natural, Gastric Stable, Food Additives, Colourants and Novel Functional Foods - COLORSPORE - - EC:FP7:KBBE2008-06-01 - 2011-11-30 - 207948 - VALID
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Food Research International
Food Research International, 2013, 51 (2), pp.914-923. ⟨10.1016/j.foodres.2013.02.003⟩
Foodservice Research International
Foodservice Research International, Wiley-Blackwell, 2013, ⟨10.1016/j.foodres.2013.02.003⟩
Foodservice Research International, Wiley-Blackwell, 2013, 51 (2), pp.914-923. ⟨10.1016/j.foodres.2013.02.003⟩
Foodservice Research International, 2013, 51 (2), pp.914-923. ⟨10.1016/j.foodres.2013.02.003⟩
Food Research International, Elsevier, 2013, 51 (2), pp.914-923. ⟨10.1016/j.foodres.2013.02.003⟩
ISSN: 0963-9969
1524-8275
1745-4506
DOI: 10.1016/j.foodres.2013.02.003⟩
Popis: International audience; The main human sources of carotenoids are fruits and vegetables. Some bacteria also synthesise carotenoids that can have peculiar chemical structures that raise the question of their bioavailability in humans. Bacillus indicus HU36 and Bacillus firmus GB1 strains contain glycosyl carotenoids that are partially acylated by linear fatty acids. The aim of the present study was to assess the bioaccessibility, the uptake efficiency and the tissue distribution of these bacterial carotenoids. β-carotene was used as a model carotenoid for comparisons. Results of in vitro digestion experiments showed that bioaccessibility of purified extracts of bacterial carotenoids was considerably higher (about 4.5 times as high) than that of pure β-carotene. Bacterial carotenoids were also bioaccessible when digested from their natural matrices, but about 2 times less than their purified extracts. Bacterial carotenoids were absorbed by Caco-2 with similar efficiency as β-carotene, i.e. about 10%. Bacterial carotenoids were recovered in significant amounts in their native chemical forms in plasma, liver and in adipose tissue of rats, which were force-fed for 3 days with either bacterial carotenoid extracts or lyophilised bacteria. Bacterial carotenoids were found at higher concentrations in rat tissues than β-carotene, about 2–3 times for GB1 carotenoids and 9 times for HU36 carotenoids. They were also more recovered in adipose tissue than β-carotene. In conclusion, glycosyl ca-rotenoids from the HU36 and GB1 Bacillus strains are readily bioavailable. This is due in part to their higher bioaccessibility but perhaps also due to their easier accumulation in tissues.
Databáze: OpenAIRE
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