Supplementary Methods, Tables 1 - 4, Figures 1 - 10 from Isolation of a Novel Thioflavin S–Derived Compound That Inhibits BAG-1–Mediated Protein Interactions and Targets BRAF Inhibitor–Resistant Cell Lines

Autor: Jakob Troppmair, Hermann Stuppner, Ramsey I. Cutress, Graham Packham, Gerhard Wolber, Sana Khalid, Muhammad Imtiaz Ashraf, Katarzyna Koziel, Stefan Schwaiger, Martin Deutsch, Maria Salomé Gachet, Emmanouil S. Papadakis, Marion Enthammer
Rok vydání: 2023
DOI: 10.1158/1535-7163.22498449
Popis: PDF file - 1877K, Supplementary Methods; Supplementary Table 1: 1H and 13C NMR shifts of Thio-2; Supplementary Table 2: 1H and 13C NMR shifts of Thio-3; Supplementary Table 3: 1H and 13C NMR shifts of Thio-5; Supplementary Table 4: 1H and 13C NMR shifts of Thio-6; Supplementary Figure 1: Spectral data Thio-2; Supplementary Figure 2: Spectral data Thio-3; Supplementry Figure 3: Spectral data Thio-5; Supplementary Figure 4: Spectral data Thio-2; Supplementary Figure 5: Cancer cell growth inhibition by Thio-2; Supplementary Figure 6: Effect of Thio-2 on intracellular signaling; Supplementary Figure 7: Effect of Thio-2 on cell survival; Supplementary Figure 8: Effect of Thio-2 on cell proliferation; Supplementary Figure 9: Thio-2 and BRAF protein stability; Supplementary Figure 10: Effect of Thio-2 protein-protein interaction (PPI)
Databáze: OpenAIRE