Recent applications in natural product synthesis of dihydro-furan and -pyran formation by ring-closing alkene metathesis
| Autor: | Peter W. Smith, David M. Hodgson, Reece Jacques, Claire E. Sear, Aubert Ribaucourt, Nicholas A. Parker, Ritashree Pal |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Biological Products Natural product 010405 organic chemistry Chemistry Alkene Organic Chemistry Context (language use) Chemistry Techniques Synthetic Alkenes 010402 general chemistry Metathesis Ring (chemistry) 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Pyran Organic chemistry Physical and Theoretical Chemistry Furans Alkene formation Pyrans |
| Zdroj: | Organic and Biomolecular Chemistry. 14(25) |
| ISSN: | 1477-0539 1477-0520 |
| Popis: | In the last two decades, alkene metathesis has risen in prominence to become a significant synthetic strategy for alkene formation. Many total syntheses of natural products have used this transformation. We review the use, from 2003 to 2015, of ring-closing alkene metathesis (RCM) for the generation of dihydro-furans or -pyrans in natural product synthesis. The strategies used to assemble the RCM precursors and the subsequent use of the newly formed unsaturation will also be highlighted and placed in context. |
| Databáze: | OpenAIRE |
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