Effect of baseline glomerular filtration rate on renal function following stenting for atherosclerotic renal artery stenosis

Autor:	Won Heum Shim, Beom Seok Kim, Hyung Jung Oh, Tae Hyun Yoo, Donghoon Choi, Jae Hyun Chang, Shin Wook Kang, Ho Yung Lee, Kyu Hun Choi
Rok vydání:	2010
Předmět:	Male medicine.medical_specialty Percutaneous Urology Renal artery angioplasty Renal function Renal Artery Obstruction urologic and male genital diseases Atherosclerotic renal artery stenosis Humans Medicine In patient Retrospective Studies business.industry Treatment options Mean age Middle Aged Atherosclerosis Surgery Nephrology Chronic renal failure Female Stents business Glomerular Filtration Rate
Zdroj:	Scandinavian Journal of Urology and Nephrology. 44:169-174
ISSN:	1651-2065 0036-5599
DOI:	10.3109/00365591003636570
Popis:	Percutaneous transluminal renal artery angioplasty and stenting (PTRAS) is one treatment option for atherosclerotic renal artery stenosis (ARAS). However, factors predicting the outcome remain controversial. This study investigated the effect of the baseline glomerular filtration rate (GFR) on renal function after PTRAS in patients with ARAS.Patients who underwent PTRAS due to significant ARAS (luminal narrowingor = 60%) were enrolled. The patients were divided into control (n = 57; estimated GFR (eGFR)or = 60 ml/min/1.73 m(2)) and chronic renal failure (CRF) groups (n = 53; eGFR60 ml/min/1.73 m(2)), according to the baseline eGFR.The mean age at the time of PTRAS was 62 +/- 9 years, and the mean duration of follow-up was 50 +/- 26 months. There was a significant decrease in eGFR after PTRAS in the control group, whereas the CRF group showed no significant change in eGFR. The percentage change in eGFR was negatively correlated with the baseline eGFR (r = -0.274, p = 0.004). Multivariate linear regression revealed that only baseline eGFR predicted the change in eGFR (p = 0.032).PTRAS was more effective at preserving renal function in patients with moderately impaired renal function. Thus, baseline GFR may indicate the expected renal function outcome after PTRAS.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8563042c2919df511be41b3ef09002c3 https://doi.org/10.3109/00365591003636570 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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