Identification of novel single nucleotide polymorphisms in the PRKAG3 gene of Pakistani river buffalo
| Autor: | Tanveer Hussain, Waqas Ahmad Khan, Masroor Ellahi Babar, Asif Nadeem, Faiz M. M. T. Marikar, Ali Raza Awan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
AMPK
0301 basic medicine animal diseases Single-nucleotide polymorphism Biology Genome 03 medical and health sciences Exon single nucleotide polymorphism parasitic diseases Pakistan Gene Genetics lcsh:Veterinary medicine General Veterinary 0402 animal and dairy science Intron food and beverages 04 agricultural and veterinary sciences PRKAG3 Milk production 040201 dairy & animal science River buffalo 030104 developmental biology lcsh:SF600-1100 Identification (biology) river buffalo geographic locations |
| Zdroj: | Bulgarian Journal of Veterinary Medicine, Vol 22, Iss 3, Pp 353-358 (2019) |
| ISSN: | 1313-3543 1311-1477 |
| Popis: | Pakistani river buffalo is classified in five breeds out of which Kundi buffalo has been least documented. This study is designed to find single nucleotide polymorphisms (SNPs) in exonic and in-tronic regions of PRKAG3 (AMP-activated, Gamma3 non-catalytic subunit) gene in the Kundi buf-falo. The PRKAG3 gene of 95 animals each from Kundi and Nili-Ravi were sequenced for identifica-tion of novel SNPs. Comparing with the Nili Ravi breed of buffalo PRKAG3 gene, six SNP sites were identified in the Kundi buffalo. The novel SNPs found in this work can function as a genomic indicator for genetic-phenotypic relationship of PRKAG3 gene with milk and meat production in buffalo. This is the first report of SNPs in PRKAG3 gene of Kundi Buffalo. |
| Databáze: | OpenAIRE |
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