Organization of medial elastin at aortic junctions in sheep and lambs
| Autor: | Barwick Se, Roach Mr, van Baardwijk C |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Pathology
medicine.medical_specialty Physiology Aorta Thoracic Intercostal Muscles Kidney Fetus Tongue Pregnancy Physiology (medical) medicine.artery medicine Animals Pharmacology Aorta Sheep biology Abdominal aorta Age Factors General Medicine Anatomy Elastin medicine.anatomical_structure Circulatory system cardiovascular system biology.protein Ultrastructure Female Blood vessel Artery |
| Zdroj: | Canadian journal of physiology and pharmacology. 63(7) |
| ISSN: | 0008-4212 |
| Popis: | Aortas from four sheep and three fetal lambs were fixed at physiological pressure in 10% neutral buffered formalin. The regions with branches were serially sectioned in either cross or longitudinal section at 7-μm intervals and stained for elastin with Gomori–aldehyde–fuchsin. A large model of one aortointercostal junction was made from Plexiglas to show that bundles of elastin appeared to be continuous from the aorta into the branch. These bundles were then studied from large photomicrographs of the other junctions. At the intercostals and lumbars, the elastin lamellae ran continuously from the outer third of the media into the branch. There was often an added "pad" of elastin and other acellular material on the flow divider (distal lip). The large muscular branches which arose from the abdominal aorta have much less elastin than the intercostals. In them the aortic elastin appears to merge into a raphe on the proximal and lateral sides of the junction, with a very abrupt transition. A "tongue" of muscle from the branch often penetrated into the media of the aorta distally. Occasionally a small acellular cap was seen on the apex of the flow divider. There were few significant differences between the lambs and the sheep, probably because embryologically the arteries develop very early. The proximal and distal lips of all junctions were easily distinguished from each other, and the small and large branches were also different. We suspect these regions may respond differently to pressure, but we did not test this hypothesis. |
| Databáze: | OpenAIRE |
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