Prevention of venous thrombosis in patients with acute intracerebral hemorrhage
| Autor: | Lacut, Karine, Bressollette, Luc, Le Gal, Grégoire, Etienne, Edith, De Tinteniac, Anne, Renault, Anne, Rouhart, François, Besson, G., Garcia, Jean-François, Mottier, Dominique, Oger, Emmanuel, Renseigné, Non |
|---|---|
| Přispěvatelé: | Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Université de Brest (UBO)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de Médecine Interne et Pneumologie [Brest] (DMIP - Brest), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service de Neurologie [Brest] |
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
MESH: Cerebral Hemorrhage MESH: Heparin Deep vein Intermittent pneumatic compression MESH: Femoral Vein 030204 cardiovascular system & hematology MESH: Hypertension 0302 clinical medicine MESH: Aged 80 and over Risk Factors MESH: Risk Factors Medicine MESH: Intermittent Pneumatic Compression Devices MESH: Treatment Outcome Aged 80 and over Venous Thrombosis MESH: Aged MESH: Middle Aged Middle Aged Thrombosis 3. Good health Pulmonary embolism Causality Venous thrombosis medicine.anatomical_structure Treatment Outcome Anesthesia Acute Disease Hypertension MESH: Acute Disease Female medicine.symptom medicine.medical_specialty MESH: Causality MESH: Anticoagulants Asymptomatic 03 medical and health sciences Humans MESH: Patient Selection cardiovascular diseases Mortality Intermittent Pneumatic Compression Devices Aged Cerebral Hemorrhage Intracerebral hemorrhage MESH: Humans MESH: Mortality business.industry Vascular disease Heparin Patient Selection MESH: Bandages Anticoagulants Femoral Vein medicine.disease Bandages MESH: Male Surgery MESH: Venous Thrombosis Neurology (clinical) business MESH: Female 030217 neurology & neurosurgery [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Neurology Neurology, American Academy of Neurology, 2005, 65 (6), pp.865-9. ⟨10.1212/01.wnl.0000176073.80532.a2⟩ |
| ISSN: | 0028-3878 1526-632X |
| Popis: | International audience; OBJECTIVE: To assess intermittent pneumatic compression (IPC) in the prevention of venous thromboembolism (VTE). METHODS: The authors randomly allocated patients with a documented intracerebral hemorrhage (ICH) to elastic stockings (ES) alone or combined with IPC. The primary outcome was a combined criteria assessed at day 10: a symptomatic and well-documented VTE, or a death arising before day 10 and related to pulmonary embolism (PE), or an asymptomatic deep vein thrombosis (DVT) of the lower limbs detected by compression ultrasonography (CUS). Outcome assessment was blinded. RESULTS: One hundred fifty-one patients were randomized; 133 (88%) patients were evaluated at day 10. No clinical suspicion of VTE arose before day 10. Fourteen patients died before having a CUS but no death was definitely related to PE. Fourteen asymptomatic DVT were detected by CUS: three (4.7%) in the ES + IPC group (all distal) and 11 (15.9%) in the ES group (three proximal and eight distal). ES combined with IPC is associated with a reduced risk of asymptomatic DVT compared to ES alone: relative risk, 0.29 (95% CI 0.08 to 1.00). CONCLUSIONS: Asymptomatic deep vein thrombosis (DVT) was detected at day 10 in 15.9% of patients wearing elastic stockings alone. Intermittent pneumatic compression significantly decreased the occurrence of asymptomatic DVT for patients with intracerebral hemorrhage. |
| Databáze: | OpenAIRE |
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