Anaplastic Transformation in Verrucous Carcinoma of the Oral Cavity After Radiation Therapy
| Autor: | Frederick T. Kraus, John C. Evans, Carlos A. Perez, William E. Powers |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Male
Larynx Pathology medicine.medical_specialty Vulva Lesion medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Epithelioma cuniculatum Aged Verrucous carcinoma business.industry Glans penis Middle Aged medicine.disease Tongue Neoplasms Squamous carcinoma Cobalt Isotopes stomatognathic diseases medicine.anatomical_structure Lip Neoplasms Carcinoma Squamous Cell Female Mouth Neoplasms Neoplasm Recurrence Local Radioisotope Teletherapy medicine.symptom business |
| Zdroj: | Radiology. 86:108-115 |
| ISSN: | 1527-1315 0033-8419 |
| Popis: | Verrucous carcinoma of the oral cavity has been established as a distinctive clinical and pathologic entity (1, 2, 11, 15). Typically, the lesion appears as a slow-growing warty mass on the gingival or buccal mucosa of an elderly patient. Histologically, it is characterized by a well differentiated pattern of squamous epithelium in abundant papillomatous hyperkeratotic folds. The tumor slowly invades deeper structures, including bone, but rarely metastasizes (1, 2, 7, 15). A predilection for the mucosa of the oral cavity of tobacco chewers has been noted (1,2, 11), but the lesion also occurs in the larynx and on the squamous mucosa of the vulva, vagina, and glans penis (15). Reports on satisfactory results of treatment of verrucous carcinoma with surgery and diathermy have appeared in the literature (11, 15, 21). Although a large number of cases of squamous carcinoma of the oral cavity have been irradiated (4, 8, 15, 19), the poor response of verrucous carcinoma to this particular method of treatment has ... |
| Databáze: | OpenAIRE |
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