An atypical case of neurotoxoplasmosis in immunocompetent patient
| Autor: | André Luiz Guimarães de Queiroz, Karlla Danielle Ferreira Lima, Carmen Lucia Penteado Lancellotti, Alex Machado Baêta, Victor Mantelatto Bonsi, Hennan Salzedas Teixeira, Bruno Shigueo Yonekura Inada |
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| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Neurotoxoplasmosis Parasitic infections R895-920 Case Report 030218 nuclear medicine & medical imaging Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid parasitic diseases Parenchyma Medicine Radiology Nuclear Medicine and imaging Pleocytosis biology medicine.diagnostic_test business.industry Brain biopsy Toxoplasma gondii Meningoencephalitis medicine.disease biology.organism_classification Toxoplasmosis Encephalitis Immunocompetent business 030217 neurology & neurosurgery |
| Zdroj: | Radiology Case Reports Radiology Case Reports, Vol 16, Iss 7, Pp 1766-1769 (2021) |
| ISSN: | 1930-0433 |
| DOI: | 10.1016/j.radcr.2021.04.013 |
| Popis: | Toxoplasmosis is an infection caused by Toxoplasma gondii, an intracellular protozoan that is often associated with immunocompromised patients and is rare in immunocompetent. A 60-year-old man was admitted with a history of 2 days of headache and right-sided weakness. There was no history of fever, surgeries, or any other comorbid illness. Cerebrospinal fluid showed just mild pleocytosis with 15 cells/mm3, predominantly lymphomononuclear. MRI showed Peripheral enhancing lesion with central diffusion restriction and perivascular enhancing lesion with restricted diffusion with vasogenic edema and leptomeningeal enhancement in the white matter. Viral serologies, tumor markers, protein electrophoresis were normal. The patient was submitted to brain biopsy, revealing necrotic brain parenchyma with predominantly acute inflammation, with diffuse encephalitis pattern, and cysts with bradyzoites (cystozoites) of Toxoplasma gondii in the brain parenchyma. The central nervous system infection by Toxoplasma gondii can present as meningoencephalitis during primary infection in an immunocompetent, although it is rare. Central nervous system lymphoma is the main differential diagnosis of neurotoxoplasmosis by imaging, especially in our case. |
| Databáze: | OpenAIRE |
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