Hypocalcemic Cardiomyopathy - a Rare Heart Failure Etiology in Adult
| Autor: | Irinel-Raluca Parepa, I Tica, L. Mazilu, C Voinea, Andra-Iulia Suceveanu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Ejection fraction Endocrine and Autonomic Systems business.industry Sinus tachycardia Endocrinology Diabetes and Metabolism Diastole Cardiomyopathy Case Report 030209 endocrinology & metabolism Dilated cardiomyopathy 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences 0302 clinical medicine Endocrinology medicine.anatomical_structure Hypoparathyroidism Ventricle Internal medicine Heart failure medicine Cardiology medicine.symptom business |
| Zdroj: | Acta Endocrinologica (Bucharest). 15:107-112 |
| ISSN: | 1843-066X 1841-0987 |
| DOI: | 10.4183/aeb.2019.107 |
| Popis: | Introduction Heart failure and dilated cardiomyopathy (DCM) in adults are rarely caused by hypoparathyroidism induced hypocalcemia. Case report Female patient, 40 years old, diabetic, with previous history of thyroidectomy for Graves' disease, was hospitalized for syncope and symptoms of heart failure. ECG revealed sinus tachycardia, long QT, negative T from V1 up to V4. Chest X-ray, cardiac ultrasound and contrast cardiac MRI confirmed dilated left chambers, severe systolic dysfunction of the left ventricle (left ventricle ejection fraction=15%) due to diffuse hypokinesia and restrictive type of diastolic dysfunction. Patient status insignificantly improved with specific heart failure depletion treatment but important signs of hypocalcemia occurred. Low levels of total and ionic serum calcium were detected (total serum calcium 3.6 mg/dL, ionic calcium=2.2 mg/dL) along with low serum levels of parathormone (10 pg/mL) and high level of phosphatemia (6.4 mg/dL). After one month of parenteral treatment with calcium and oral vitamin D, hypocalcemic signs disappeared and heart failure significantly improved. Conclusion This rare adult condition is refractory to heart failure conventional therapy but promptly responds to restoration of normocalcemia. It is important to be aware of this pathophysiological setting, in order to treat it correctly. |
| Databáze: | OpenAIRE |
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