Inadvertent Methylergonovine Administration to a Neonate
| Autor: | Charles W. O'Connell, Bryan Corbett, Mallory A. Boutin, Nabil I. Fatayerji, Charles W. Sauer |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pediatrics
medicine.medical_specialty Vitamin K Neonatal intensive care unit medicine.disease_cause Injections Intramuscular 03 medical and health sciences 0302 clinical medicine Methylergonovine Oxytocics 030225 pediatrics Intensive care Humans Medication Errors Medicine 030212 general & internal medicine Adverse effect business.industry Poisoning Infant Newborn Articles General Medicine medicine.disease Uterine atony Term Infant Anesthesia Accidental Intensive Care Neonatal Female Respiratory Insufficiency business Nasal cannula |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| DOI: | 10.12659/ajcr.900263 |
| Popis: | Patient: Male, Newborn Final Diagnosis: Accidental methylergonovine poisoning Symptoms: Respiratory distress Medication: — Clinical Procedure: — Specialty: Pediatrics and Neonatology Objective: Diagnostic/therapeutic accidents Background: Methylergonovine is an ergot alkaloid used to treat post-partum hemorrhage secondary to uterine atony. Mistaking methylergonovine for vitamin K with accidental administration to the neonate is a rare iatrogenic illness occurring almost exclusively in the delivery room setting. Complications of ergot alkaloids in neonates include respiratory depression, seizures, and death. Case Report: A term infant was inadvertently given 0.1 mg of methylergonovine intramuscularly in the right thigh. The error was only noted when the vial of medication was scanned, after administration, identifying it as methylergonovine rather than vitamin K. The local poison center was notified, and the infant was transferred to the neonatal intensive care unit for observation. Two hours after transfer, the infant was noted to have oxygen desaturations and required oxygen via nasal cannula. Supplemental oxygen was continued for 4 hours until the neonate was able to maintain normal oxygen saturations in room air. Feeding was started by 10 hours of life, and the infant was discharged home in good condition after a 72-hour stay without further complications. Conclusions: Because of the potential for serious adverse events, vigilance is required to prevent accidental administration of methylergonovine to the neonate as a result of possible confusion with vitamin K in the early post-partum period. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|