Cutaneous Bipolaris Infection in a Neutropenic Patient with Acute Lymphoblastic Leukemia
| Autor: | Donna, Bilu, Saeid, Movahedi-Lankarani, Rebecca A, Kazin, Christine, Shields, Margaret, Moresi |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Antifungal Agents Neutropenia Osteolysis Dermatology Wrist Contiguity (probability theory) Ascomycota Prednisone Amphotericin B medicine Dermatomycoses Humans business.industry Osteomyelitis Ulna Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Skeleton (computer programming) Surgery Cheek medicine.anatomical_structure Child Preschool business Pyoderma gangrenosum medicine.drug |
| Zdroj: | Journal of Cutaneous Medicine and Surgery. 8:446-449 |
| ISSN: | 1615-7109 1203-4754 |
| Popis: | Pyoderma gangrenosum (PG) has been described in association with sterile neutrophilic infiltration of several organ systems, including the skeleton. The most frequent cause of bony disease in PG has been chronic, recurrent, multifocal osteomyelitis, a sterile inflammatory disease of children and young adults mimicking infectious osteomyelitis. Bony erosions have been only rarely described in direct contiguity to a PG ulcer. We report a 53-year-old woman with recurrent PG who developed an erosion of the distal ulna adjacent to a PG ulcer. The patient responded to high-dose prednisone, and a repeat radiograph of the wrist four months later was normal. This case demonstrates another example of cortical osteolysis directly adjacent to a PG ulcer in which the bony changes may be neutrophil-induced. |
| Databáze: | OpenAIRE |
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