Is Aerobic or Resistance Training the Most Effective Exercise Modality for Improving Lower Extremity Physical Function and Perceived Fatigue in People With Multiple Sclerosis?:A Systematic Review and Meta-analysis
| Autor: | Luke J Connolly, Laurits Taul-Madsen, Jenny Freeman, Rachel Dennett, Lars G. Hvid, Ulrik Dalgas |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty Multiple Sclerosis FITNESS medicine.medical_treatment MEDLINE Physical Therapy Sports Therapy and Rehabilitation law.invention CAPACITY Multiple sclerosis 03 medical and health sciences MUSCLE STRENGTH 0302 clinical medicine Randomized controlled trial Rating scale law QUALITY-OF-LIFE Exercise/physiology medicine Aerobic exercise Humans Multiple Sclerosis/physiopathology Exercise Fatigue Randomized Controlled Trials as Topic Rehabilitation business.industry DISABILITY ENDURANCE Resistance Training ADULTS WALKING ABILITY Confidence interval Lower Extremity/physiopathology CLINICALLY MEANINGFUL Lower Extremity Data extraction MS PATIENTS Meta-analysis Physical therapy Systematic review Fatigue/physiopathology 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | Taul-Madsen, L, Connolly, L, Dennett, R, Freeman, J, Dalgas, U & Hvid, L G 2021, ' Is Aerobic or Resistance Training the Most Effective Exercise Modality for Improving Lower Extremity Physical Function and Perceived Fatigue in People With Multiple Sclerosis? A Systematic Review and Meta-analysis ', Archives of Physical Medicine and Rehabilitation, vol. 102, no. 10, pp. 2032-2048 . https://doi.org/10.1016/j.apmr.2021.03.026 |
| DOI: | 10.1016/j.apmr.2021.03.026 |
| Popis: | Objective The purpose of this systematic review was to investigate whether aerobic training (AT) or resistance training (RT) is most effective in terms of improving lower limb physical function and perceived fatigue in persons with multiple sclerosis (PwMS). Data Sources Nine databases (MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health, Allied and Complementary Medicine Database, Physiotherapy Evidence Database, SPORTDiscus, PsycINFO, Web of Science, and Scopus) were electronically searched in April 2020. Study Selection Included studies were randomized controlled trials (RCTs) involving PwMS attending 1 of 2 exercise interventions: AT or RT. Studies had to include at least 1 objective or self-reported outcome of lower extremity physical function and/or perceived fatigue. Data Extraction Data were extracted using a customized spreadsheet, which included detailed information on patient characteristics, interventions, and outcomes. The methodological quality of the included studies was independently assessed by 2 reviewers using the Tool for Assessment of Study Quality for Reporting on Exercise rating scale. Data Synthesis Twenty-seven articles reporting data from 22 RCTS (AT=14, RT=8) including 966 PwMS. The 2 modalities were found to be equally effective in terms of improving short walk test (AT: effect size [ES]=0.33 [95% confidence interval (CI), −1.49 to 2.06]; RT: ES=0.27 [95% CI, 0.07-0.47]) and long walk test performance (AT: ES=0.37 [95% CI, −0.04 to 0.78]; RT: ES=0.36 [95% CI, −0.35 to 1.08]), as well as in reducing perceived fatigue (AT: ES=−0.61 [95% CI, −1.10 to −0.11]; RT: ES=−0.41 [95% CI, −0.80 to −0.02]). Findings on other functional mobility tests along with self-reported walking performance were sparse and inconclusive. Conclusions AT and RT appear equally highly effective in terms of improving lower extremity physical function and perceived fatigue in PwMS. Clinicians can thus use either modality to target impairments in these outcomes. In a future perspective, head-to-head exercise modality studies are warranted. Future MS exercise studies are further encouraged to adapt a consensus “core battery” of physical function tests to facilitate a detailed comparison of results across modalities. |
| Databáze: | OpenAIRE |
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