| Autor: |
Federica Di Nicolantonio, Ryan B. Corcoran, Salvatore Siena, Alberto Bardelli, Andrea Sartore-Bianchi, Jeffrey A. Engelman, Josep Tabernero, Jan H.M. Schellens, René Bernards, Margherita Gallicchio, Julieta Grasselli, Giulia Siravegna, Mauro Truini, Giorgio Corti, Michael Linnebacher, Carlotta Cancelliere, Michela Buscarino, Jason T. Godfrey, Valentina Boscaro, Giovanni Crisafulli, Alice Bartolini, Robin M.J.M. van Geel, Elena Elez, Giulia Marzolla, Genny Filiciotto, Andrea Cassingena, Sabrina Arena, Emanuele Valtorta, Ludovic Barault, Erin M. Sennott, Daniele Oddo |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22413582 |
| Popis: |
Supplementary Tables S1-S3 - List of drug concentrations to generate resistant cell lines (S1); Drug concentrations applied in the screening depicted in Figure 6 (S2); Primers for gene amplification and sequencing (S3). Supplementary Figure S1. Synergistic activity of targeted therapy combinations in BRAF mutant colorectal cancer cells. Supplementary Figure S2. Amplification of mutant BRAF V600E confers resistance to combined EGFR and MEK targeting in colorectal cancer cells. Supplemental Figure S3. Cytotoxicity induced by ERK inhibition in VACO432 resistant to BRAF combination therapies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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