Commentaries on viewpoint: does SIRT1 determine exercise-induced skeletal muscle mitochondrial biogenesis: differences between in vitro and in vivo experiments?
| Autor: | Keir J, Menzies, Beatrice, Chabi, David A, Hood, Simon, Schenk, Andrew, Philp, Andrew, Philip, Valdir A, Braga, Drielle Dantas, Guimaraes |
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| Přispěvatelé: | York University, Dynamique Musculaire et Métabolisme (DMEM), Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
endocrine system diseases
Physiology [SDV]Life Sciences [q-bio] Mitochondrion Biology environment and public health 03 medical and health sciences 0302 clinical medicine Sirtuin 1 In vivo Physiology (medical) medicine Animals Humans [INFO]Computer Science [cs] Muscle Skeletal Exercise ComputingMilieux_MISCELLANEOUS 030304 developmental biology 0303 health sciences Protein level Skeletal muscle In vitro Cell biology Mitochondria enzymes and coenzymes (carbohydrates) medicine.anatomical_structure Mitochondrial biogenesis biology.protein biological phenomena cell phenomena and immunity hormones hormone substitutes and hormone antagonists 030217 neurology & neurosurgery |
| Zdroj: | Canadian Journal of Applied Physiology Canadian Journal of Applied Physiology, Human Kinetics, 2012, 112 (5), pp.929-930. ⟨10.1152/japplphysiol.00094.2012⟩ |
| ISSN: | 1066-7814 1543-2718 |
| DOI: | 10.1152/japplphysiol.00094.2012⟩ |
| Popis: | {#article-title-2} to the editor: We applaud Gurd et al. ([2][1]) for attempting to resolve the function of SIRT1 in exercise-induced mitochondrial biogenesis. Uncertainty about the role of SIRT1 has arisen because of 1 ) discrepancies between SIRT1 protein level and mitochondrial content, which |
| Databáze: | OpenAIRE |
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