Vitamin D Levels in Asymptomatic Children and Adolescents with Atopy during the COVID-19 Era
| Autor: | Vasiliki Vlacha, Luminita A. Stanciu, Raluca Maria Pop, Gavriela Feketea, Georgios Tsiros, Panagiota Voila, Mihnea Zdrenghea, Ioana Corina Bocsan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) atopy Medicine (miscellaneous) vitamin D Immunoglobulin E Gastroenterology Asymptomatic Article vitamin D deficiency Atopy 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Vitamin D and neurology 030212 general & internal medicine biology business.industry COVID-19 Eosinophil medicine.disease Increased IgE level medicine.anatomical_structure 030228 respiratory system biology.protein Medicine medicine.symptom business |
| Zdroj: | Journal of Personalized Medicine, Vol 11, Iss 712, p 712 (2021) Journal of Personalized Medicine Volume 11 Issue 8 |
| ISSN: | 2075-4426 |
| DOI: | 10.3390/jpm11080712 |
| Popis: | This study assessed vitamin D status in asymptomatic children and adolescents in Greece, with and without atopy, and possible changes during the coronavirus disease 2019 (COVID-19) pandemic. Serum levels of 25-hydroxy-vitamin D (25(OH)D) and total immunoglobulin E (IgE), and eosinophil count were measured in 340 asymptomatic children and adolescents (155 males, 185 females), mean age 8.6 ± 4.6 years, recruited over a period of 24 months (February 2019–January 2021). Atopy, defined by high level of IgE for age, was associated with vitamin D deficient status (p = 0.041). Subjects with and without atopy showed similar rates of insufficient and normal levels of 25(OH)D. The median level of 25(OH)D was significantly higher in subjects recruited during the pandemic, when home confinement rules were observed, than before the pandemic, and significantly more children had normal levels of 25(OH)D (p < 0.001), but no differences were noticed for IgE levels or eosinophil count. These results support a link between vitamin D and allergic and infectious inflammations, and specifically the association of vitamin D deficiency with asymptomatic atopy, defined as increased IgE level for age. |
| Databáze: | OpenAIRE |
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