Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de Chile
| Autor: | Tatiana Figueroa-Reyes, Eloy Mansilla L, Jorge Nogales-Gaete, David Sáez M, Iris Delgado B, Rodrigo Sánchez |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2011 |
| Předmět: |
Pediatrics
medicine.medical_specialty Plasminogen activators business.industry medicine.medical_treatment General Medicine Thrombolysis medicine.disease Stroke Thrombolytic therapy Prospective analysis Public hospital Medicine business Prospective cohort study Severe disability Acute ischemic stroke After treatment |
| Zdroj: | Revista médica de Chile v.139 n.9 2011 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Background: The only accepted treatment for acute ischemic stroke is thrombolysis with recombinant tissue plasminogen activator (t-PA). It was implemented in Chile in 1996, although its use was mainly restricted in Chile to private clinics. Recently, at year 2009, we have implemented this treatment in a public hospital. Aim : To describe the results of treatment of acute ischemic stroke with t-PA in a public hospital in Chile. Material and Methods : Prospective analysis of all eligible patients with acute ischemic stroke that were admitted within 4 hours of its onset and had no contraindications for thrombolysis. Results : In an eight months period, a total of 19 intravenous thrombolyses were performed in 12 males and seven females aged 28 to 79 years old. The mean lapse between onset of symptoms and onset of thrombo- lysis was 190 ± 57 min. Results were favorable, according to Rankin and National Institute of Health Stroke scales. Ninety days after treatment, 63% of patients had minimal or absent disability, 26% had moderate disability and only one (5%) had severe disability. One patient had a clinically not significant intracranial hemorrhage and one patient died six days after thrombolysis. Conclusions : These results indicate that thrombolysis can be successfully implemented in Chilean public hospitals. The limitations for its use in this setting are mostly administrative |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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